Round 17 in the NRL concludes with the Rabbitohs hosting the Penrith Panthers after the Tigers beat the Knights.
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Tigers take down Knights in bottom-of-the-table showdown
Wests Tigers took a step towards avoiding their first NRL wooden spoon, beating Newcastle 33-12 on Sunday.
The win puts the Tigers two points above the Knights at the bottom of the ladder with a bye in hand.
The Tigers' attack looked the most cohesive it has at any point under new coach Ivan Cleary as Luke Brooks and Tuimoala Lolohea combined well.
Moses Suli had the best game of his young career.
New South Wales State of Origin prop Aaron Woods was also in form with four offloads and 161 metres in a dominant display.
Suli, 19, busted through seven tackles and had one try assist at left centre as Tigers fans got their best glimpse of the future of the club at Hunter Stadium.
Rabbitohs v Panthers