Savannah Guthrie has urged "anyone with information" about her mother's disappearance to contact the authorities

In a statement given to the programme, she said: "On behalf of our family, I want to thank everyone for the thoughts, prayers and messages of support.

"Right now, our focus remains on the safe return of our dear Nancy.

"We thank law enforcement for their hard work on this case, and encourage anyone with information to contact the Pima County Sheriff's Department."

Nancy has been missing since around 9:45pm on Saturday (31.02.26) in Arizona, and authorities have launched an extensive search after she was reported missing around noon the following day.

On Sunday (01.02.26), the Pima County Sheriff's Department revealed she had last been seen at her residence in the Catalina Foothills area.

In a briefing later in the day, Sheriff Chris Nanos said: "We hope we find her safe and sound, but we are very concerned."

He explained that foul play could not be ruled out due to "concerning evidence", but did not elaborate.

He explained: "You don't typically get the sheriff out at a scene like this, but it's very concerning what we're learning from the house.

"This one stood out because of what was described to us at the scene and what we found and located just in looking at the scene."

Although Nanos wouldn't reveal what was found at the home, he did confirm that homicide detectives have been called.

He added: "It's not standard. Typically, our homicide team comes out when we have a homicide, a body.

"This one was done simply because of what the surveyors were telling us."

The search has included ground crews with headlamps, dog teams, the Sheriff's Department plane, and drones, while deputies also checked in with hospitals and medical transport teams.

While Nancy has no cognitive issues, she is considered a "vulnerable adult" due to her age and physical mobility.

Nanos explained: "Miss Guthrie is 84 years old and is not in good physical health.

"She has no cognitive issues at all - just some physical ailments that limit her ability to move around."