Rob Kardashian has taken a shot at ex-girlfriend Adrienne Bailon on Twitter

Khloe tweeted the jibe on Wednesday afternoon (30.07.14) just hours after sister Kim Kardashian, 33, leapt to Rob's defence and scolded Adrienne for kicking their sibling - who has been battling depression over his substantial weight gain - "when he's down".

The former 3LW singer, who dated the reality TV star for two years from 2007 to 2009, recently gave a tell-all interview in which she accused Rob of cheating on her and claims that appearing on the famous family's E! show had a negative impact on her career as a singer and actress.

She said: "To be stuck with that Kardashian label, that was so hurtful to me and to my career. I probably realised that too late - not that it would've affected my decisions in terms of who I dated, but it would've affected my decision to appear on the show."

Kim was the first Kardashian to hit back at Adrienne, tweeting: "Funny how she says being with a Kardashian hurt her career yet the only reason she has this article is bc she is talking about a Kardashian

"So sad when people try to kick my brother when he is down #FamilyForever (sic)"

Khloe, 30, later echoed Kim's sentiments and added: "thought her and I were cool SMH [shake my head] (sic)"