The Israeli military says it has struck six airports in western, eastern and central Iran, destroying warplanes and helicopters.
US President Donald Trump has appeared to reopen the door on seeking regime change in Iran, taking to his social media platform to question if it would "make Iran great again".
It comes after Iran's president said the United States must receive a "response to their aggression" after yesterday's attacks, as new satellite imagery shows damage at the Fordow nuclear site.
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