Michelle and Barack Obama were due to meet Rob Reiner and his wife Michele on the day they died

During an appearance on Jimmy Kimmel Live!, Michelle shared: "We've known them for many, many years, and we were supposed to be seeing them that night."

Barack previously took to social media to pay a glowing tribute to the acclaimed filmmaker.

The former President wrote on X: "Michelle and I are heartbroken by the tragic passing of Rob Reiner and his beloved wife, Michele. Rob's achievements in film and television gave us some of our most cherished stories on screen. But beneath all of the stories he produced was a deep belief in the goodness of people-and a lifelong commitment to putting that belief into action. Together, he and his wife lived lives defined by purpose. They will be remembered for the values they championed and the countless people they inspired. We send our deepest condolences to all who loved them."

US President Donald Trump also took to social media to react to the tragedy.

The billionaire businessman wrote on the Truth Social platform: "Rob Reiner, a tortured and struggling, but once very talented movie director and comedy star, has passed away, together with his wife, Michele, reportedly due to the anger he caused others through his massive, unyielding, and incurable affliction with a mind crippling disease known as TRUMP DERANGEMENT SYNDROME, sometimes referred to as TDS.

"He was known to have driven people CRAZY by his raging obsession of President Donald J. Trump, with his obvious paranoia reaching new heights as the Trump Administration surpassed all goals and expectations of greatness, and with the Golden Age of America upon us, perhaps like never before. May Rob and Michele rest in peace (sic)"

Nick Reiner, the couple's 32-year-old son, is set to be formally charged with the murders of his parents.